In some parts of the world, specially australia and some islands of the west indies, it is known as papaw, or pawpaw, names which are better limited to the very different, mainly wild asimina triloba dunal, belonging to the annonaceae. The medicinal properties of papaya fruit and other parts of the plant are also well known in traditional system of medicine. Antiulcerogenic activity of carica papaya seed in rats. The present study was conducted to evaluate the antioxidant and immunostimulant effects of the carica papaya fruit aqueous extract cpf, caricaceae against acrylamide induced oxidative stress and improvement of immune functions which affected by free radicals liberating acrylamide in rats. Antioxidant activity of papaya seed extracts article pdf available in molecules 168. Carica papaya have been reported to posses potent mosquito larvicidal activity. Evaluation of mosquito larvicidal effect of carica coden. At concentration of 200 papaya seed extract, papaya peel extract exhibited a gml, the te values decreased significantly in the significantly higher p inhibition activity at the order of bha 1478 1. The larvicidal activity of selected parts of carica papaya extracts against aedesaegypti are given in table 2. The purpose of this paper is to investigate various extracts of annona squamosa l annonanceae and carica papaya l caricaceae seeds for their antioxidant activity, free radical scavenging ability, total phenolic and flavonoid contents. The mosquito larvicidal activity reported in the present study could be due to any of the bioactive compounds mentioned above. We found that the antioxidant activity of vitamin c and carica papaya seeds extract is high when added during the recovery after oxidative stress for vitamin c and during oxidative stress for carica papaya seeds extract. Classification for kingdom plantae down to species carica papaya l. Ginsburg2 1the hematology branch, hebrew university hadassah medical center, jerusalem, israel 2the institute for dental sciences, faculty of dental medicine, hebrew university hadassah medical center, jerusalem, israel oxidative stress has been recognized to play.
Antioxidant activity of seed extracts of annona squamosa and carica papaya. Carica papaya cp otherwise known as the papaya pear is found in most tropical and subtropical countries of the world. Phytochemical screening, antioxidant activity, and. The gastric juice and mucus parameters were evaluated using the. The highland papayas, vasconcellea, are considered the nearest relatives to carica papaya although the relationship is not close aradhya et al.
Carica papaya caricaceae is believed to probably originate from southern mexico and costa rica and then introduced as a plantation crop in all tropical and subtropical regions krishna et al. The present study evaluated the antioxidant and immunostimulant activities of carica papaya l aqueous extract against acrylamide toxicity. The melons are usually picked in a green state and allowed to ripen. Papaya as an alternative antibiotic for the development of newer antibacterial agents. Sp in jayapura, papua indonesia henny sesanti1, arsunan, a. Caricaceae papaya originates from tropical central and south america, ranging from mexico to bolivia. Two methods namely dpph radical scavenging keywords antioxidant activity total phenolic content total flavonoid content carica papaya.
About the classification report about the classification download. Carica papaya, solo, solomix, antimicrobial, antioxidant 1. Drying methods had significant p antioxidant phytochemicals, that is, total phenol, tannin, total flavonoid, total carotenoid, and vitamin c levels of the seeds, with freezedrying. Antihypertensive effect of carica papaya via a reduction in ace activity and improved baroreflex. The antioxidant activity was studied at 517 nm by dpph free radical scavenging activity. In some parts of asia, the young leaves of the papaya are steamed and eaten like spinach. Carica papaya, belongs to the family of caricaceae, and several. Pdf an investigation of the antioxidant property of carica papaya. The purpose of the present study was to evaluate the gastroprotective and healing effects of the methanolic extract of the seed of the papaya carica papaya l. Cells posses a variety of primary and secondary defenses against lipid peroxidation and other deleterious effect of oxidative damage. Papayas uc davis western institute for food safety and. Papaya is commonly known for its food and nutritional values throughout the world. The results showed that the highest antioxidant activity through. Phytochemical screening and hypoglycemic activity of.
Abstract background papaya is widely grown in malaysia and. Pdf pawpaw carica papaya linn seeds, peels and leaves are well known for their medicinal and potent pharmacological values. Phytochemical screening and hypoglycemic activity of carica papaya leaf in streptozotocininduced diabetic rats. Since, each part of papaya tree possesses economic value, it is grown on commercial scale. Studies on the effect of the different modes of extraction. Carica papaya is widely used in folk medicine as herbal remedy to prevent, protect against, and cure several diseases. Phytochemical screening, antimicrobial and antioxidant. Introduction medicinal plant is an important element of indigenous medical systems in all over the world. Introduction biological activity is the basis for traditional medicine, which uses the pharmacological efficacy of natural compounds present in herbal preparations for treating human diseases 1. Effects of drying on total polyphenols content and antioxidant. Administration dependent antioxidant effect of carica. Introduction to papaya, carica papaya, as a food of the. Pdf antioxidant activity of seed extracts of annona.
When ripe, the flesh is sweet and juicy and similar in taste to other melons. Carica papaya, aerial parts, anticancer activity, phytoconstituents. Casein assay wavelength enzyme activity carica papaya ananas comosus actinidia deliciosa 280 280 280 2. Pharmacological activity of each division of carica papaya whole carica papaya has a unique pharmacological uses 4. Experimental animals received 25200 mgkg orally of the extracts or saline control group and the reference group received 5 mg kg of indomethacin. U v vis spectral analysis was done by using u v vis spectrophotometer between 300nm. For each extract a phytochemical screening was performed. The results showed petroleum ether extract of the rind of raw carica papaya fruit exhibited significant anti malarial activity. Anticancer activity of carica papaya extracts in and. Pdf nutraceutical and antioxidant properties of the seeds, leaves. Ms showed at least 15 components, esters were the most abundant group of compounds. The antiinflammatory activity of an ethanolic extract of carica papaya leaves was investigated in rats using carrageenan induced paw oedema, cotton pellet granuloma and formaldehyde induced arthritis models. Pdf northeast india is rich in medicinal plants and is unique in the diversity and.
Antibacterial activity of seed and leaf extract of carica papaya var. Antifungal activity of carica papaya linkedin slideshare. This family comprises of 31 species in the four genera. Antioxidant analysis of different parts of carica papaya abstract this study was conducted to compare the total antioxidant activity taa, total phenolic content tpc and total flavonoid content tfc from the different parts of papaya tree including their ripe and unripe fruit, seeds and the young leaves. The spectrophotometer absorbance at 595nm for the carica papaya extract is given in table 2. The antioxidant effect of fermented papaya preparation in. Mountain papayas carica pubescens spread limitedly and can only adapt in the highland environment. The papaya plant, carica papaya careica papiuh, is a shortlived herbaceous plant native to tropical climates in the americas. We investigated the antiplasmodial properties of crude extracts from carica papaya leaves to trace the activity through bioassayguided fractionation.
Carica papaya seed isolates and concentrate demonstrated potent antioxidant activity and could be of nutraceutical importance in the pharmaceutical and food. This fruit, however, is now found yearround throughout tropical and equatorial regions. But the home of the papaya is tropical latin america. Pdf antioxidant potential of carica papaya peel and seed. The greatest antiplasmodial activity was observed in the ethyl acetate crude extract. Carica is a genus of flowering plants in the family caricaceae including c. As a crop, papaya is characterized by high yield and precociousness since it begins scaled production before the first year. Potential test of papaya leaf and seed extract carica papaya as larvicides against anopheles mosquito larvae mortality. Diabetes the killer disease known worldwide has been implicated to generate oxidative stress and carica papaya has been suggested to manage this effect.
Administration dependent antioxidant effect of carica papaya. Antioxidant analysis of different parts of carica papaya. The antioxidant activities of solo and solomix showed ic50 of 1. Papaya is the most widely cultivated and best known species. Effect of drying methods on the phytochemicals composition. Models of acute gastric ulcer induction by ethanol and indomethacin and of chronic ulcer by acetic acid were used. The fruits of papaya are much sought after by human as valuable foodstuff and have antihypertensive activity. Carica papaya, alkaloids, antioxidants, antehelminthes, herbs 1. A2 and hasanuddin ishak3 1 environmental health department, polytechnic of health, jayapura, papua province, indonesia. Antibacterial activity of seed and leaf extract of carica. Casein assay subathra et al 2012 the enzyme activity of the crude enzyme extracts was determined. In vivo antiprotozoal activity of the chloroform extract from carica papaya seeds against amastigote stage of trypanosoma cruzi during indeterminate and. Carica papaya is widely grown now and used in different for the purpose of food as well as decorative purpose. Antioxidant activity of fermented papaya preparation fpp in the absence and presence of saliva.
Fruit harvest produces various byproducts as plants are removed after finishing the production cycle approximately 2 years of continuous. Click on names to expand them, and on p for plants profiles. Papayas are a fleshy fruit that were nicknamed tree melons by early european explorers, but papaya fruit is actually considered to be a berry. About four species are found of which carica papaya, linn. Pusa dwarf linn jyotsna kiran peter, yashab kumar, priyanka pandey and harison masih department of microbiology and fermentation technology, jsbb, shiats deemed to be university, naini, up, india 211008.
These curative properties are based on the presence in different parts of the plant of phytochemical nutrients with antioxidant effect. The effect of in vitro digestion on the antioxidant activity of fruit. This study demonstrates the efficacy of ethanolic leaf extracts of c. Different concentrations of carica papaya leaf extract wild species were prepared and allowed to stand for 30 minutes at room temperature. Potential test of papaya leaf and seed extract carica. This study was therefore aimed at evaluating the antioxidant activity of c. The antioxidant effect of fermented papaya preparation in the oral cavity q1 e. Papaya is a small, bushy tree with a hollow trunk, large palmate leaves, and oblong smoothskinned fruits melons.
Introduction cancer is a leading cause of death worldwide, it is a dreadful disease, and combating this disease is of great importance to public health. Antioxidant effect of aqueous carica papaya seeds extract. Effect of carica papaya leaf extract capsule on platelet. Review on nutritional, medicinal and pharmacological. Sd on the phytochemicals composition and antioxidant activities of carica papaya seeds, a medicinal plant, was investigated. This study was designed to explore the preliminary phytochemical and physicochemical analysis of carica papaya l. Papayas are the fourth most traded tropical fruit following. Caricaceae is a genus of rapid growing unbranched small trees, native to tropical america and widely distributed in the tropics.
1074 817 1162 1111 29 665 219 100 1097 208 1375 1180 544 1209 1149 346 856 402 916 5 540 249 183 913 1333 604 275 1503 332 73 826 934 1218 2 912 362 1125 204 1174 605 1031 297 1237